Nebivolol HCl

Catalog No.: A10630

Nebivolol HCl

Nebivolol HCl Chemical Structure

CAS NO. 152520-56-4

Nebivolol hydrochloride is t a highly selective antagonist of the β1-adrenoceptor (Ki = 0.88 nM, β2-adrenoceptor Ki = 48 nM).

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10 mg
25 mg
50 mg
100 mg
10mM * 1mL in DMSO
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  • Giovanni Bocci, .et al. Virtual and In Vitro Antiviral Screening Revive Therapeutic Drugs for COVID-19, ACS Pharmacol Transl Sci, 2020, Oct 14

Biological Activity

Nebivolol hydrochloride is t a highly selective antagonist of the β1-adrenoceptor (Ki = 0.88 nM, β2-adrenoceptor Ki = 48 nM).
0.8 nM
In vitro DMSO 81 mg/mL (183.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.63 mL 113.15 mL 226.3 mL
0.5 mM 4.53 mL 22.63 mL 45.26 mL
1 mM 2.26 mL 11.31 mL 22.63 mL
5 mM 0.45 mL 2.26 mL 4.53 mL

*The above data is based on the productmolecular weight 441.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10630
CAS No. 152520-56-4
Formula C22H25F2NO4.HCl
M. Wt 441.9
Purity >98%
Synonyms R-67145
SMILES C1CC2=C(C=CC(=C2)F)O[[email protected]]1[[email protected]](CNC[[email protected]@H]([[email protected]@H]3CCC4=C(O3)C=CC(=C4)F)O)O.Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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