Catalog No.: A13738

Beta-1 adrenergic receptor blocker


Nebivolol Chemical Structure

CAS NO. 118457-14-0

Nebivolol is a selective inhibits Beta-1 adrenergic receptor with IC50 of 0.8 nM

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Biological Activity

Nebivolol is a selective inhibits Beta-1 adrenergic receptor with IC50 of 0.8 nM
In vitro DMSO 75 mg/mL (184.99 mM)
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.66 mL 123.32 mL 246.65 mL
0.5 mM 4.93 mL 24.66 mL 49.33 mL
1 mM 2.47 mL 12.33 mL 24.66 mL
5 mM 0.49 mL 2.47 mL 4.93 mL

*The above data is based on the productmolecular weight 405.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13738
Actions Blocker
CAS No. 118457-14-0
Formula C22H25F2NO4
M. Wt 405.44
Solubility DMSO
Purity >98%
Synonyms Nebilet, Bystolic, R 065824, R065824, R-065824
SMILES C1CC2=C(C=CC(=C2)F)O[[email protected]]1[[email protected]](CNC[[email protected]@H]([[email protected]@H]3CCC4=C(O3)C=CC(=C4)F)O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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