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$0.00 Biological Activity
Nemorubicin is an anticancer drug with IC50 value of 0.08 uM. It is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.54 mL | 77.68 mL | 155.37 mL |
| 0.5 mM | 3.11 mL | 15.54 mL | 31.07 mL |
| 1 mM | 1.55 mL | 7.77 mL | 15.54 mL |
| 5 mM | 0.31 mL | 1.55 mL | 3.11 mL |
*The above data is based on the productmolecular weight 643.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14363 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 108852-90-0 |
| Formula | C32H37NO13 |
| M. Wt | 643.64 |
| Purity | >98% |
| Synonyms | PNU152243A, PNU-152243A, PNU 152243A, Nemorubicin, methoxymorpholinyl-doxorubicin |
| SMILES | O=C1C2=C(O)C(C[[email protected]](C(CO)=O)(O)C[[email protected]@H]3O[[email protected]]4C[[email protected]](N5C[[email protected]@H](OC)OCC5)[[email protected]](O)[[email protected]](C)O4)=C3C(O)=C2C(C6=C1C=CC=C6OC)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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