Nemorubicin

Catalog No.: A14363

Topoisomerase II inhibitor

Nemorubicin

Nemorubicin Chemical Structure

CAS NO. 108852-90-0

Nemorubicin is an anticancer drug with IC50 value of 0.08 uM. It is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition.

Availability: In stock

Package Price Qty
1 mg
$520.00
5 mg
$950.00
10 mg
$1,450.00
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Biological Activity

Nemorubicin is an anticancer drug with IC50 value of 0.08 uM. It is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.54 mL 77.68 mL 155.37 mL
0.5 mM 3.11 mL 15.54 mL 31.07 mL
1 mM 1.55 mL 7.77 mL 15.54 mL
5 mM 0.31 mL 1.55 mL 3.11 mL

*The above data is based on the productmolecular weight 643.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14363
Actions Inhibitor
CAS No. 108852-90-0
Formula C32H37NO13
M. Wt 643.64
Purity >98%
Synonyms PNU152243A, PNU-152243A, PNU 152243A, Nemorubicin, methoxymorpholinyl-doxorubicin
SMILES O=C1C2=C(O)C(C[[email protected]](C(CO)=O)(O)C[[email protected]@H]3O[[email protected]]4C[[email protected]](N5C[[email protected]@H](OC)OCC5)[[email protected]](O)[[email protected]](C)O4)=C3C(O)=C2C(C6=C1C=CC=C6OC)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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