NHPI-PEG3-C2-Pfp ester

Catalog No.: A43291
ADC linker
NHPI-PEG3-C2-Pfp ester is a non-cleavable linker composed of a three-unit polyethylene glycol (PEG) chain designed for use in antibody-drug conjugates (ADCs). This reagent facilitates the stable attachment of drug molecules to antibodies, enhancing therapeutic efficacy while minimizing off-target effects. Its unique structure allows for improved solubility and biocompatibility, making it suitable for various applications in drug development and cancer therapeutics.
Grouped product items
Size Price Stock Qty
5mg
$50.00
In stock
10mg
$75.00
In stock
25mg
$120.00
In stock
50mg
$175.00
In stock
100mg
$260.00
In stock
250mg
$575.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNHPI-PEG3-C2-Pfp ester is a non-cleavable linker composed of a three-unit polyethylene glycol (PEG) chain designed for use in antibody-drug conjugates (ADCs). This reagent facilitates the stable attachment of drug molecules to antibodies, enhancing therapeutic efficacy while minimizing off-target effects. Its unique structure allows for improved solubility and biocompatibility, making it suitable for various applications in drug development and cancer therapeutics.
Product Information
Catalog NumA43291
FormulaC23H20F5NO8
Molecular Weight533.40
CAS Number2101206-87-3
SMILESO=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCON(C(C2=C3C=CC=C2)=O)C3=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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