Nidulalin A

Name: Nidulalin A
Brand: Adooq Bioscience
SKU: A57192
Rating: 5 (288 reviews)

Catalog No.: A57192

DNA Topoisomerase II Inhibitor

Nidulalin A is a selective inhibitor of DNA topoisomerase II, exhibiting an IC50 value of 2.2 μM. Additionally, it demonstrates significantly less activity against DNA topoisomerase I, with an IC50 of 172 μM. Due to its DNA-damaging effects, Nidulalin A shows notable cytotoxicity, making it a valuable compound for research in cancer biology and drug development.

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Nidulalin A 162901-86-2 DNA Topoisomerase II Inhibitor

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Biological Activity

Description	Nidulalin A is a selective inhibitor of DNA topoisomerase II, exhibiting an IC50 value of 2.2 μM. Additionally, it demonstrates significantly less activity against DNA topoisomerase I, with an IC50 of 172 μM. Due to its DNA-damaging effects, Nidulalin A shows notable cytotoxicity, making it a valuable compound for research in cancer biology and drug development.

Product Information

Catalog Num	A57192
Formula	C16H14O6
Molecular Weight	302.28
CAS Number	162901-86-2
SMILES	COC([C@]12C(C(C3=C(O)C=C(C)C=C3O2)=O)=CC=C[C@H]1O)=O

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