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NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.26 mL | 126.32 mL | 252.63 mL |
| 0.5 mM | 5.05 mL | 25.26 mL | 50.53 mL |
| 1 mM | 2.53 mL | 12.63 mL | 25.26 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.05 mL |
*The above data is based on the productmolecular weight 395.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13993 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 395.83 |
| Formula | C22H18ClNO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 208237-49-4 |
| Synonyms | NK-314, NK 314 |
| SMILES | OC1=C(OC)C=CC2=C(C=CC3C4C=C5C(OCO5)=C3)C4=[N+]6C(CCC6)=C12.[Cl-] |
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