NK314

Catalog No.: A13993

Topoisomerase II inhibitor

NK314 Chemical Structure

CAS NO. 208237-49-4

NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes.

Availability: Out of stock

Package Price
5 mg
$220.00
10 mg
$400.00
25 mg
$900.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.26 mL 126.32 mL 252.63 mL
0.5 mM 5.05 mL 25.26 mL 50.53 mL
1 mM 2.53 mL 12.63 mL 25.26 mL
5 mM 0.51 mL 2.53 mL 5.05 mL

*The above data is based on the productmolecular weight 395.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13993
Actions Inhibitor
M. Wt 395.83
Formula C22H18ClNO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 208237-49-4
Synonyms NK-314, NK 314
SMILES OC1=C(OC)C=CC2=C(C=CC3C4C=C5C(OCO5)=C3)C4=[N+]6C(CCC6)=C12.[Cl-]

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