Biological Activity
NKY 80 is an inhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM respectively).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 43.62 mL | 218.12 mL | 436.24 mL |
0.5 mM | 8.72 mL | 43.62 mL | 87.25 mL |
1 mM | 4.36 mL | 21.81 mL | 43.62 mL |
5 mM | 0.87 mL | 4.36 mL | 8.72 mL |
*The above data is based on the productmolecular weight 229.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13586 |
---|---|
Actions | Inhibitor |
CAS No. | 299442-43-6 |
Formula | C12H11N3O2 |
M. Wt | 229.23 |
Purity | >98% |
Synonyms | NKY80, NKY-80 |
SMILES | C1C(CC(=O)C2=CN=C(N=C21)N)C3=CC=CO3 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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