NLG919

Catalog No.: A14322

IDO inhibitor

NLG919

NLG919 Chemical Structure

CAS NO. 1402836-58-1

NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.

Availability: In stock

Package Price Qty
25 mg
$180.00
50 mg
$240.00
100 mg
$420.00
10mM * 1mL in DMSO
$79.00
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Biological Activity

NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities.
Targets
IDO (Cell-free assay) IDO (Cell-free assay)
75 nM(EC50)75 nM(EC50)
In vitro DMSO 15 mg/mL heating (53.11 mM)
Water <1 mg/mL (<1 mM)
Ethanol 56 mg/mL heating (198.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.41 mL 177.07 mL 354.13 mL
0.5 mM 7.08 mL 35.41 mL 70.83 mL
1 mM 3.54 mL 17.71 mL 35.41 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14322
Actions Inhibitor
M. Wt 282.38
Formula C18H22N2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1402836-58-1
Synonyms NLG 919, NLG-919
SMILES C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O

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