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Biological Activity
Nortadalafil is demethyl Tadalafil, which is a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED) under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.64 mL | 133.2 mL | 266.4 mL |
| 0.5 mM | 5.33 mL | 26.64 mL | 53.28 mL |
| 1 mM | 2.66 mL | 13.32 mL | 26.64 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.33 mL |
*The above data is based on the productmolecular weight 375.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15191 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 171596-36-4 |
| Formula | C21H17N3O4 |
| M. Wt | 375.38 |
| Purity | >98% |
| Synonyms | Demethyl Tadalafil |
| SMILES | C1C2C(=O)NCC(=O)N2C(C3=C1C4=CC=CC=C4N3)C5=CC6=C(C=C5)OCO6 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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