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Biological Activity
NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.45 mL | 112.26 mL | 224.53 mL |
| 0.5 mM | 4.49 mL | 22.45 mL | 44.91 mL |
| 1 mM | 2.25 mL | 11.23 mL | 22.45 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11505 |
|---|---|
| Actions | Antagonist |
| CAS No. | 324523-20-8 |
| Formula | C24H26Cl2N2O2 |
| M. Wt | 445.38 |
| Purity | >98% |
| Synonyms | SB-262470A hydrochloride |
| SMILES | N#CC1=C(OC[[email protected]@H](CNC(C)(C)CC2=CC=C3C=CC=CC3=C2)O)C=CC=C1Cl.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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