NS11394

Catalog No.: A21425

GABA(A) receptor modulator

NS11394

NS11394 Chemical Structure

CAS NO. 951650-22-9

NS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$155.00
50 mg
$460.00
100 mg
$920.00
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Biological Activity

NS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA(A) alpha subunit-containing receptors.
In vitro DMSO 69 mg/mL (195.23 mM)
Water Insoluble
Ethanol 69 mg/mL (195.23 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.29 mL 141.47 mL 282.95 mL
0.5 mM 5.66 mL 28.29 mL 56.59 mL
1 mM 2.83 mL 14.15 mL 28.29 mL
5 mM 0.57 mL 2.83 mL 5.66 mL

*The above data is based on the productmolecular weight 353.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21425
Actions Modulator
CAS No. 951650-22-9
Formula C23H19N3O
M. Wt 353.42
Solubility DMSO
Purity >98%
Synonyms NS 11394, NS-11394
SMILES N#CC1=CC=CC=C1C2=CC=CC(N3C4=CC=C(C(C)(O)C)C=C4N=C3)=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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