NSC-23766 HCl

Catalog No.: A13975

Rac GTPase inhibitor

NSC-23766 HCl

NSC-23766 HCl Chemical Structure

CAS NO. 1177865-17-6

NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).

Availability: Out of stock

Package Price
5 mg
$45.00
10 mg
$80.00
25 mg
$150.00
10mM * 1mL in DMSO
$58.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).
Targets
Rac GTPase (Cell-free assay)
50 μM
In vitro DMSO 100 mg/mL heating (188.33 mM)
Water 100 mg/mL heating (188.33 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.83 mL 94.16 mL 188.32 mL
0.5 mM 3.77 mL 18.83 mL 37.66 mL
1 mM 1.88 mL 9.42 mL 18.83 mL
5 mM 0.38 mL 1.88 mL 3.77 mL

*The above data is based on the productmolecular weight 531. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13975
Actions Inhibitor
M. Wt 531
Formula C24H35N7.3HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1177865-17-6
Synonyms NSC 23766, NSC23766
SMILES CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl.Cl.Cl

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