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NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).
Targets
| Rac GTPase (Cell-free assay) | ||||
| 50 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.83 mL | 94.16 mL | 188.32 mL |
| 0.5 mM | 3.77 mL | 18.83 mL | 37.66 mL |
| 1 mM | 1.88 mL | 9.42 mL | 18.83 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.77 mL |
*The above data is based on the productmolecular weight 531. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13975 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1177865-17-6 |
| Formula | C24H35N7.3HCl |
| M. Wt | 531 |
| Purity | >98% |
| Synonyms | NSC 23766, NSC23766 |
| SMILES | CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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