NSC 23766

Catalog No.: A12546

Rac1 activation inhibitor

NSC 23766

NSC 23766 Chemical Structure

CAS NO. 733767-34-5

NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation.

Availability: In stock

Package Price Qty
10 mg
$80.00
25 mg
$150.00
50 mg
$250.00
100 mg
$400.00
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Biological Activity

NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.83 mL 94.17 mL 188.33 mL
0.5 mM 3.77 mL 18.83 mL 37.67 mL
1 mM 1.88 mL 9.42 mL 18.83 mL
5 mM 0.38 mL 1.88 mL 3.77 mL

*The above data is based on the productmolecular weight 530.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12546
Actions Inhibitor
M. Wt 530.97
Formula C24H35N7.3HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 733767-34-5
Synonyms NSC-23766, NSC23766
SMILES CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl

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