NSC 23766

Name: NSC 23766
SKU: A12546
Price: 35 USD
Rating: 5 (288 reviews)

Catalog No.: A12546

Rac1 activation inhibitor

NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation.

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Grouped product items
Size	Price	Stock
2mg	$35.00	In stock
5mg	$60.00	In stock
10mg	$75.00	In stock
25mg	$145.00	In stock
50mg	$245.00	In stock
100mg	$395.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription	NSC 23766 is a selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation.

Product Information

Catalog Num	A12546
Formula	C24H35N7
Molecular Weight	421.6
CAS Number	733767-34-5
SMILES	CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C
Synonyms	NSC-23766, NSC23766
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	Warmed: 92 mg/mL (173.26 mM)
	Water	Warmed: 92 mg/mL (173.26 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.72 mL	118.6 mL	237.19 mL
0.5 mM	4.74 mL	23.72 mL	47.44 mL
1 mM	2.37 mL	11.86 mL	23.72 mL
5 mM	0.47 mL	2.37 mL	4.74 mL

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