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NSC 663284 is a potent, cell-permeable, and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for Cdc25A, Cdc25B2, and Cdc25C, respectively).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.08 mL | 155.38 mL | 310.75 mL |
| 0.5 mM | 6.22 mL | 31.08 mL | 62.15 mL |
| 1 mM | 3.11 mL | 15.54 mL | 31.08 mL |
| 5 mM | 0.62 mL | 3.11 mL | 6.22 mL |
*The above data is based on the productmolecular weight 321.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13524 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 321.8 |
| Formula | C15H16ClN3O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 383907-43-5 |
| Synonyms | SPS8I, DA-3003-1, Cdc25 Phosphatase Inhibitor II |
| SMILES | C1COCCN1CCNC2=C(C(=O)C3=C(C2=O)N=CC=C3)Cl |
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