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Biological Activity
NU6102 is selective for CDK1 and CDK2 compared to CDK4/D1 (IC50=1.6 μM), DYRK1A (IC50=0.9 μM), PDK1 (IC50=0.8 μM) and ROCKII (IC50=0.6 μM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.84 mL | 124.22 mL | 248.45 mL |
| 0.5 mM | 4.97 mL | 24.84 mL | 49.69 mL |
| 1 mM | 2.48 mL | 12.42 mL | 24.84 mL |
| 5 mM | 0.5 mL | 2.48 mL | 4.97 mL |
*The above data is based on the productmolecular weight 402.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12438 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 444722-95-6 |
| Formula | C18H22N6O3S |
| M. Wt | 402.5 |
| Purity | >98% |
| Synonyms | NU6102,NU-6102 |
| SMILES | C1CCC(CC1)COC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)S(=O)(=O)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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