Catalog No.: A17022

CDK9 Inhibitor


NVP-2 Chemical Structure

CAS NO. 1263373-43-8

NVP-2 is a potent and selective ATP-competitive CDK9 inhibitor with IC50 value of 0.5 nM.

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Biological Activity

NVP-2 is a potent and selective ATP-competitive CDK9 inhibitor with IC50 value of 0.5 nM.
In vitro DMSO 95 mg/mL (185.16 mM)
Water Insoluble
Ethanol 95 mg/mL (185.16 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.49 mL 97.45 mL 194.9 mL
0.5 mM 3.9 mL 19.49 mL 38.98 mL
1 mM 1.95 mL 9.75 mL 19.49 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 513.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17022
Actions Inhibitor
CAS No. 1263373-43-8
Formula C27H37ClN6O2
M. Wt 513.08
Purity >98%
Synonyms NVP 2, NVP2
SMILES COC[[email protected]](N[[email protected]]1CC[[email protected]](NC2=CC(C3=NC(NCC4(C#N)CCOCC4)=CC=C3)=C(C=N2)Cl)CC1)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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