NVP-BHG712

Catalog No.: A10661
EphB4 inhibitor
NVP-BHG712 is a selective inhibitor of EphB4 kinase that exhibits selectivity for EphB4 over more than 40 other kinases in vitro, including FGFR3.
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Product Name Price Stock Qty
NVP-BHG712 5mg
Special Price $64.00 Regular Price $80.00
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NVP-BHG712 10mg
Special Price $120.00 Regular Price $150.00
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NVP-BHG712 50mg
Special Price $480.00 Regular Price $600.00
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NVP-BHG712 100mg
Special Price $800.00 Regular Price $1,000.00
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NVP-BHG712 10mM * 1mL in DMSO
Special Price $96.00 Regular Price $120.00
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Adooq Products cited in reputable paper
Adooq's NVP-BHG712 has been cited by 1 publications
  • Y Kaibori, .et al. , the FASEB Journal, 2019, Jan 22:fj201801519RR PMID: 30668924
  • Biological Activity
    Discription NVP-BHG712 is a selective inhibitor of EphB4 kinase that exhibits selectivity for EphB4 over more than 40 other kinases in vitro, including FGFR3.
    Targets
    Target Value
    Product Information
    Catalog Num A10661
    Formula C26H20F3N7O
    Molecular Weight 503.5
    CAS Number 940310-85-0
    SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=NC(=NC4=C3C=NN4C)C5=CN=CC=C5
    Synonyms BHG712
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 90 mg/mL (178.75 mM)
    Water Insoluble
    Ethanol 3 mg/mL (5.95 mM)
    In vivo NMP+PEG300 (10+90, v+v) 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.86 mL 99.3 mL 198.61 mL
    0.5 mM 3.97 mL 19.86 mL 39.72 mL
    1 mM 1.99 mL 9.93 mL 19.86 mL
    5 mM 0.4 mL 1.99 mL 3.97 mL
    Useful Calculator

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