NVP-DFF332 is a potent HIF2α inhibitor that demonstrates inhibitory activity with IC50 values of 9 nM for HIF2α SPA, 37 nM for HIF2α iScript, and 246 nM for HIF2α HRE RGA. This compound exhibits significant antitumor effects, making it valuable for cancer research focused on hypoxia-inducible factors. Its ability to modulate HIF2α activity positions NVP-DFF332 as a promising tool for studying tumor biology and therapeutic interventions.
NVP-DFF332 is a potent HIF2α inhibitor that demonstrates inhibitory activity with IC50 values of 9 nM for HIF2α SPA, 37 nM for HIF2α iScript, and 246 nM for HIF2α HRE RGA. This compound exhibits significant antitumor effects, making it valuable for cancer research focused on hypoxia-inducible factors. Its ability to modulate HIF2α activity positions NVP-DFF332 as a promising tool for studying tumor biology and therapeutic interventions.
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