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Biological Activity
NVP DPP 728 dihydrochloride is a potent and orally active inhibitor of dipeptidyl peptidase (DPP)-IV with Ki and IC50 values of 11 nM and 14 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.93 mL | 134.67 mL | 269.35 mL |
| 0.5 mM | 5.39 mL | 26.93 mL | 53.87 mL |
| 1 mM | 2.69 mL | 13.47 mL | 26.93 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
*The above data is based on the productmolecular weight 371.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15320 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 247016-69-9 |
| Formula | C15H18N6O.2HCl |
| M. Wt | 371.27 |
| Purity | >98% |
| SMILES | C1CC(N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C#N.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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