NY0116

Catalog No.: A62159
NMUR2 Agonist
NY0116 is an agonist of the neuromedin U receptor 2 (NMUR2), exhibiting an EC50 of 13.61 μM for hNMUR2 and 27.76 μM for hNMUR1. This compound effectively reduces cAMP levels while enhancing calcium signaling in HEK293 cells stably expressing NMUR2. NY0116 is suitable for research applications involving neuropeptide signaling pathways and their physiological implications.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNY0116 is an agonist of the neuromedin U receptor 2 (NMUR2), exhibiting an EC50 of 13.61 μM for hNMUR2 and 27.76 μM for hNMUR1. This compound effectively reduces cAMP levels while enhancing calcium signaling in HEK293 cells stably expressing NMUR2. NY0116 is suitable for research applications involving neuropeptide signaling pathways and their physiological implications.
Product Information
Catalog NumA62159
FormulaC22H23N3O
Molecular Weight345.44
CAS Number1003000-59-6
SMILESNC(NCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=N
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