O-Desmethyl gefitinib

Name: O-Desmethyl gefitinib
Brand: Adooq Bioscience
SKU: A24176
Rating: 5 (288 reviews)

Catalog No.: A24176

EGFR inhibitor

O-Desmethyl gefitinib is an active plasma metabolite of gefitinib, formed via CYP2D6-mediated metabolism. It retains EGFR inhibitory activity with an IC50 of 36 nM in subcellular assays.

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O-Desmethyl gefitinib 847949-49-9 EGFR inhibitor

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Grouped product items
Size	Price	Stock
5mg	$126.00	In stock
10mg	$217.00	In stock
50mg	$644.00	In stock
100mg	$1,260.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description	O-Desmethyl gefitinib is an active plasma metabolite of gefitinib, formed via CYP2D6-mediated metabolism. It retains EGFR inhibitory activity with an IC50 of 36 nM in subcellular assays.

Product Information

Catalog Num	A24176
Formula	C21H22ClFN4O3
Molecular Weight	432.88
CAS Number	847949-49-9
SMILES	OC1=CC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C=C1OCCCN4CCOCC4
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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