O-Desmethyl Midostaurin is the active metabolite of Midostaurin, produced through cytochrome P450 liver enzyme metabolism. This compound serves as a valuable biomarker for assessing Midostaurin metabolism in vivo. Additionally, Midostaurin itself is known for being a multi-targeted protein kinase inhibitor, demonstrating IC50 values ranging from 22-500 nM. O-Desmethyl Midostaurin can be utilized in various biological studies concerning drug metabolism and pharmacokinetics.
O-Desmethyl Midostaurin is the active metabolite of Midostaurin, produced through cytochrome P450 liver enzyme metabolism. This compound serves as a valuable biomarker for assessing Midostaurin metabolism in vivo. Additionally, Midostaurin itself is known for being a multi-targeted protein kinase inhibitor, demonstrating IC50 values ranging from 22-500 nM. O-Desmethyl Midostaurin can be utilized in various biological studies concerning drug metabolism and pharmacokinetics.
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