OAB-14 is a derivative of Bexarotene that enhances the clearance of β-amyloid in APP/PS1 transgenic mice, addressing Alzheimer's disease-related pathologies and cognitive deficits. This compound demonstrates the ability to improve the functionality of the endosomal-autophagic-lysosomal pathway, making it a valuable tool for research into Alzheimer's disease mechanisms and potential therapeutic interventions.
OAB-14 is a derivative of Bexarotene that enhances the clearance of β-amyloid in APP/PS1 transgenic mice, addressing Alzheimer's disease-related pathologies and cognitive deficits. This compound demonstrates the ability to improve the functionality of the endosomal-autophagic-lysosomal pathway, making it a valuable tool for research into Alzheimer's disease mechanisms and potential therapeutic interventions.
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