Ochnaflavone is a potent inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 value of 3.45 µM. It demonstrates notable anti-inflammatory and hepatoprotective properties, effectively inhibiting both phosphatidylethanolamine (PE) degradation and carbon tetrachloride (CCl4)-induced lipid peroxidation in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone is valuable in research related to liver injury and inflammatory conditions.
Ochnaflavone is a potent inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 value of 3.45 µM. It demonstrates notable anti-inflammatory and hepatoprotective properties, effectively inhibiting both phosphatidylethanolamine (PE) degradation and carbon tetrachloride (CCl4)-induced lipid peroxidation in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone is valuable in research related to liver injury and inflammatory conditions.
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