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OHM1

Catalog No.: A75607
HIF1α CTAD Analog
OHM1 is an analog of the HIF1α C-terminal transactivation domain (CTAD) that selectively inhibits the interaction between HIF1α and the coactivators p300/CBP. With an affinity of 0.53 μM for the CH1 domain, OHM1 effectively disrupts HIF1α-mediated transcriptional activity. This compound is valuable for research applications focused on hypoxia signaling, cancer biology, and the regulation of cellular responses to oxygen levels.
OHM1 1450995-09-1 HIF1α CTAD Analog
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOHM1 is an analog of the HIF1α C-terminal transactivation domain (CTAD) that selectively inhibits the interaction between HIF1α and the coactivators p300/CBP. With an affinity of 0.53 μM for the CH1 domain, OHM1 effectively disrupts HIF1α-mediated transcriptional activity. This compound is valuable for research applications focused on hypoxia signaling, cancer biology, and the regulation of cellular responses to oxygen levels.
Product Information
Catalog NumA75607
FormulaC24H42N6O5
Molecular Weight494.63
CAS Number1450995-09-1
SMILESO=C(N)[C@@H](N1C([C@H](C)N(C([C@@H](N2C([C@H](CC(C)C)NCC2)=O)CC(C)C)=O)CC1)=O)CCC(N)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Angiogenesis > HIF/HIF Prolyl-Hydroxylase