Olmesartan medoxomil

Catalog No.: A11615

Olmesartan medoxomil

Olmesartan medoxomil Chemical Structure

CAS NO. 144689-63-4

Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.

Availability: In stock

Package Price Qty
25 mg
$50.00
50 mg
$70.00
100 mg
$121.00
200 mg
$200.00
10mM * 1mL in DMSO
$55.00
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  • Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489

Biological Activity

Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.
Targets
AT1 receptor
In vitro DMSO 89 mg/mL (159.32 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.9 mL 89.51 mL 179.02 mL
0.5 mM 3.58 mL 17.9 mL 35.8 mL
1 mM 1.79 mL 8.95 mL 17.9 mL
5 mM 0.36 mL 1.79 mL 3.58 mL

*The above data is based on the productmolecular weight 558.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11615
M. Wt 558.6
Formula C29H30N6O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 144689-63-4
Synonyms Benicar, Olmetec
SMILES CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O

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