Biological Activity
ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as ??-type platelet-derived growth factor receptor (PDGFR??).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.3 mL | 116.49 mL | 232.98 mL |
0.5 mM | 4.66 mL | 23.3 mL | 46.6 mL |
1 mM | 2.33 mL | 11.65 mL | 23.3 mL |
5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
*The above data is based on the productmolecular weight 429.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A12584 |
---|---|
Actions | Inhibitor |
M. Wt | 429.23 |
Formula | C24H27N7O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1357470-29-1 |
Synonyms | ON123300, ON 123300 |
SMILES | N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O |
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