ON123300

Catalog No.: A12584
CDK4 inhibitor?€?
ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as ??-type platelet-derived growth factor receptor (PDGFR??).
Grouped product items
Product Name Price Stock Qty
ON123300 5mg
$120.00
In stock
ON123300 10mg
$180.00
In stock
ON123300 25mg
$400.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as ??-type platelet-derived growth factor receptor (PDGFR??).
Targets
Target Value
Product Information
Catalog Num A12584
Formula C24H27N7O
Molecular Weight 429.23
CAS Number 1357470-29-1
SMILES N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O
Synonyms ON123300, ON 123300
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 26 mg/mL (60.53 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.3 mL 116.49 mL 232.98 mL
0.5 mM 4.66 mL 23.3 mL 46.6 mL
1 mM 2.33 mL 11.65 mL 23.3 mL
5 mM 0.47 mL 2.33 mL 4.66 mL
Useful Calculator

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