ORG-20241

Catalog No.: A42027
PDE3/PDE4 Inhibitor
ORG-20241 is a dual inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4). This compound exhibits a significant bronchodilator effect and effectively prevents allergen-induced airway hyperresponsiveness. Additionally, ORG-20241 significantly inhibits eosinophil infiltration at elevated concentrations. It serves as a valuable tool for research focused on asthma and related respiratory conditions.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionORG-20241 is a dual inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4). This compound exhibits a significant bronchodilator effect and effectively prevents allergen-induced airway hyperresponsiveness. Additionally, ORG-20241 significantly inhibits eosinophil infiltration at elevated concentrations. It serves as a valuable tool for research focused on asthma and related respiratory conditions.
Product Information
Catalog NumA42027
FormulaC12H13N3O3S
Molecular Weight279.31
CAS Number145261-31-0
SMILESONC(C1=NC(C2=CC(OC)=C(OC)C=C2)=CS1)=N
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