Org-9935 is a selective phosphodiesterase 3 (PDE3) inhibitor with an IC50 of 50 nM. This compound has been shown to inhibit the maturation of oocytes in naturally selected dominant follicles in rhesus macaques. Additionally, Org-9935 enhances glucose-induced insulin secretion in isolated rat islets, with an EC50 of 20 μM, making it a valuable tool for research in reproductive biology and insulin signaling pathways.
Org-9935 is a selective phosphodiesterase 3 (PDE3) inhibitor with an IC50 of 50 nM. This compound has been shown to inhibit the maturation of oocytes in naturally selected dominant follicles in rhesus macaques. Additionally, Org-9935 enhances glucose-induced insulin secretion in isolated rat islets, with an EC50 of 20 μM, making it a valuable tool for research in reproductive biology and insulin signaling pathways.
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