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ORY-1001 (RG-6016)

LSD1 Inhibitor

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Catalog No. A15893

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ORY-1001 5mg A15893-5
$150.00
ORY-1001 10mg A15893-10
$250.00
ORY-1001 25mg A15893-25
$550.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ORY-1001 is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1.

ORY-1001 (RG-6016)

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Chemical Information

Catalog Num A15893
Actions Inhibitor
M. Wt 303.27
Formula C15H22N2.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1431326-61-2
Synonyms RG6016, RG-6016
SMILES NC1CCC(N[[email protected]@H]2C[[email protected]]2C3=CC=CC=C3)CC1.Cl.Cl

Biological Activity

Description
ORY-1001 is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1.
Targets
LSD1/KDM1A
20 nM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.97 mL 164.87 mL 329.74mL
0.5 mM 6.59 mL 32.97 mL 65.95 mL
1 mM 3.3 mL 16.49 mL 32.97 mL
5 mM 0.66 mL 3.3 mL 6.59 mL

*The above data is based on the productmolecular weight 303.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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