Signaling Pathway
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| Discription | OSI-420 (Desmethyl Erlotinib,CP-473420) is an orally active EGFR tyrosin kinase inhibitor, which inhibits receptor tyrosine kinases (TKs) by inhibition of the intercellular domain . | ||
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| Catalog Num | A10678 |
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| Formula | C21H21N3O4.HCl |
| Molecular Weight | 415.9 |
| CAS Number | 183320-51-6 |
| SMILES | COCCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCO.Cl |
| Synonyms | Desmethyl Erlotinib,CP-473420 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Warmed: 75 mg/mL (180.34 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.04 mL | 120.22 mL | 240.44 mL |
| 0.5 mM | 4.81 mL | 24.04 mL | 48.09 mL |
| 1 mM | 2.4 mL | 12.02 mL | 24.04 mL |
| 5 mM | 0.48 mL | 2.4 mL | 4.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
