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Osutidine

Catalog No.: A34198
Histamine H2 Receptor Antagonist
Osutidine is a selective antagonist of the histamine H2 receptor, effectively inhibiting histamine-induced gastric acid secretion. This compound exhibits insurmountable and non-competitive inhibition, while not influencing [14C]aminopyrine accumulation prompted by carbachol or dibutyryl-cAMP. Osutidine is particularly useful for investigating gastric mucosal injury and related gastrointestinal disorders.
Osutidine 140695-21-2 Histamine H2 Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOsutidine is a selective antagonist of the histamine H2 receptor, effectively inhibiting histamine-induced gastric acid secretion. This compound exhibits insurmountable and non-competitive inhibition, while not influencing [14C]aminopyrine accumulation prompted by carbachol or dibutyryl-cAMP. Osutidine is particularly useful for investigating gastric mucosal injury and related gastrointestinal disorders.
Product Information
Catalog NumA34198
FormulaC19H28N4O5S2
Molecular Weight456.58
CAS Number140695-21-2
SMILESOC(C1=CC=C(O)C=C1)CN/C(NS(C)(=O)=O)=N\CCSCC2=CC=C(CNC)O2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Histamine Receptors