Catalog No.: A18632

SUV39H2 inhibitor


OTS186935 Chemical Structure

CAS NO. 2093400-18-9

OTS186935 is a protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM.

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5 mg

Regular Price: $350.00

Special Price $280.00

10 mg

Regular Price: $650.00

Special Price $520.00

50 mg

Regular Price: $2,000.00

Special Price $1,600.00

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  • Jennings Luu, .et al. Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model, Hum Mol Genet, 2020, Jul 21;ddaa158 PMID: 32691052

Biological Activity

OTS186935 is a protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.55 mL 107.77 mL 215.54 mL
0.5 mM 4.31 mL 21.55 mL 43.11 mL
1 mM 2.16 mL 10.78 mL 21.55 mL
5 mM 0.43 mL 2.16 mL 4.31 mL

*The above data is based on the productmolecular weight 463.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18632
Actions Inhibitor
CAS No. 2093400-18-9
Formula C25ClN5O2
M. Wt 463.96
Purity >98%
Synonyms OTS 186935, OTS-186935
SMILES COC1=C(Cl)C=C(C2=CN3C=CC(N4C[[email protected]@H](NCC5=CC=NC=C5)CC4)=CC3=N2)C(OC)=C1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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