oxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) is an NF-κB activator that functions as a key ligand for β-glycoprotein I (β(2)-GPI), derived from oxidized low-density lipoprotein (oxLDL). By promoting nuclear translocation, oxLig-1 initiates the NF-κB signaling pathway, which plays a significant role in various inflammatory processes. This compound is instrumental in research on atherosclerosis and offers insights into the mechanisms underlying lipid metabolism and cardiovascular diseases.
oxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) is an NF-κB activator that functions as a key ligand for β-glycoprotein I (β(2)-GPI), derived from oxidized low-density lipoprotein (oxLDL). By promoting nuclear translocation, oxLig-1 initiates the NF-κB signaling pathway, which plays a significant role in various inflammatory processes. This compound is instrumental in research on atherosclerosis and offers insights into the mechanisms underlying lipid metabolism and cardiovascular diseases.
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