Oxomemazine hydrochloride is a phenothiazine-derived histamine H1-receptor blocker with significant antimuscarinic properties. It acts as a selective antagonist at the muscarinic M1 receptor, exhibiting approximately 20-fold variance in affinity compared to the M2 receptor (Ki= 84 nM for M1 and Ki= 1.65 μM for M2). This compound serves as an antihistamine and anticholinergic agent, making it valuable for research focused on cough treatment and related respiratory conditions.
Oxomemazine hydrochloride is a phenothiazine-derived histamine H1-receptor blocker with significant antimuscarinic properties. It acts as a selective antagonist at the muscarinic M1 receptor, exhibiting approximately 20-fold variance in affinity compared to the M2 receptor (Ki= 84 nM for M1 and Ki= 1.65 μM for M2). This compound serves as an antihistamine and anticholinergic agent, making it valuable for research focused on cough treatment and related respiratory conditions.
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