P-CAB Agent 2 Hydrochloride is a potent potassium-competitive acid blocker targeting the H+/K+-ATPase enzyme, demonstrating an IC50 value of less than 100 nM. This reagent effectively inhibits gastric acid secretion and exhibits selective blocking of the hERG potassium channel with an IC50 of 18.69 µM. P-CAB Agent 2 Hydrochloride has been shown to have a favorable safety profile, as it demonstrates no acute toxicity while effectively suppressing histamine-induced gastric acid production. It is a valuable tool for research applications focused on gastrointestinal pharmacology.
P-CAB Agent 2 Hydrochloride is a potent potassium-competitive acid blocker targeting the H+/K+-ATPase enzyme, demonstrating an IC50 value of less than 100 nM. This reagent effectively inhibits gastric acid secretion and exhibits selective blocking of the hERG potassium channel with an IC50 of 18.69 µM. P-CAB Agent 2 Hydrochloride has been shown to have a favorable safety profile, as it demonstrates no acute toxicity while effectively suppressing histamine-induced gastric acid production. It is a valuable tool for research applications focused on gastrointestinal pharmacology.
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