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PACAP (1-38) free acid

Catalog No.: A62911
Endogenous Neuropeptide
PACAP (1-38) free acid is a desamido derivative of the endogenous neuropeptide PACAP, specifically targeting the human PAC1 receptor. It is known to stimulate cyclic AMP (cAMP) production in both neuroendocrine NS-1 cells and non-neuroendocrine HEK293 cells. This compound is valuable for research involving neuropeptide signaling pathways and their physiological roles.
PACAP (1-38) free acid 129405-61-4 Endogenous Neuropeptide
Grouped product items
Size Price Stock Qty
1mg
$80.00
In stock
5mg
$205.00
In stock
10mg
$310.00
In stock
25mg
$500.00
In stock
50mg
$705.00
In stock
100mg
$930.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPACAP (1-38) free acid is a desamido derivative of the endogenous neuropeptide PACAP, specifically targeting the human PAC1 receptor. It is known to stimulate cyclic AMP (cAMP) production in both neuroendocrine NS-1 cells and non-neuroendocrine HEK293 cells. This compound is valuable for research involving neuropeptide signaling pathways and their physiological roles.
Product Information
Catalog NumA62911
FormulaC203H330N62O54S
Molecular Weight4535.24
CAS Number129405-61-4
SequenceHis-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys
Sequence shorteningHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK
SMILES[H]N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](CC(O)=O)C(NCC(N[C@]([H])(C(N[C@@H](CC2=CC=CC=C2)C(N[C@]([H])(C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC(N)=O)=O)CCCCN)=O)C(C)C)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCCN)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)CC(C)C)=O)C(C)C)=O)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CCCCN)=O)C(C)C)=O)=O)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CO)=O)=O)CO)=O)=O)[C@H](O)C)=O)=O)[C@@H](C)CC)=O)=O)=O)CO)=O
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