Pardoprunox hydrochloride

Catalog No.: A21624

partial dopamine D2 and D3 receptor agonist

Pardoprunox hydrochloride

Pardoprunox hydrochloride Chemical Structure

CAS NO. 269718-83-4

Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
In vitro DMSO 29 mg/mL (107.51 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.07 mL 185.37 mL 370.74 mL
0.5 mM 7.41 mL 37.07 mL 74.15 mL
1 mM 3.71 mL 18.54 mL 37.07 mL
5 mM 0.74 mL 3.71 mL 7.41 mL

*The above data is based on the productmolecular weight 269.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21624
Actions Agonist
CAS No. 269718-83-4
Formula C12H16ClN3O2
M. Wt 269.73
Solubility DMSO
Purity >98%
Synonyms SLV-308 hydrochloride, SLV308, SLV 308; DU-126891 hydrochloride, DU 126891, DU126891
SMILES O=C1OC2=C(N3CCN(C)CC3)C=CC=C2N1.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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