PC Mal-NHS carbonate ester

Catalog No.: A42854
ADC Linker
PC Mal-NHS carbonate ester functions as a cleavable linker in the development of antibody-drug conjugates (ADCs). Its primary activity lies in facilitating the selective attachment of cytotoxic agents to monoclonal antibodies, allowing for targeted delivery to cancer cells. This compound is essential for advancing research in targeted therapies and improving the efficacy of cancer treatments.
Grouped product items
Size Price Stock Qty
5mg
$180.00
In stock
10mg
$295.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPC Mal-NHS carbonate ester functions as a cleavable linker in the development of antibody-drug conjugates (ADCs). Its primary activity lies in facilitating the selective attachment of cytotoxic agents to monoclonal antibodies, allowing for targeted delivery to cancer cells. This compound is essential for advancing research in targeted therapies and improving the efficacy of cancer treatments.
Product Information
Catalog NumA42854
FormulaC24H26N4O12
Molecular Weight562.48
CAS Number1408057-91-9
SMILESO=C(ON1C(CCC1=O)=O)OC(C2=CC(OC)=C(OCCCC(NCCN3C(C=CC3=O)=O)=O)C=C2[N+]([O-])=O)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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