PD-1/PD-L1-IN-23 is a potent, orally active inhibitor of the PD-1/PD-L1 interaction. As an ester proagent of L7, a benzo[c][1,2,5]oxadiazole derivative, it has been evaluated for its ability to inhibit PD-L1. This compound demonstrates significant antitumor effects in various tumor models, including syngeneic and PD-L1 humanized mice, making it a valuable tool for cancer research and the development of immune checkpoint therapies.
PD-1/PD-L1-IN-23 is a potent, orally active inhibitor of the PD-1/PD-L1 interaction. As an ester proagent of L7, a benzo[c][1,2,5]oxadiazole derivative, it has been evaluated for its ability to inhibit PD-L1. This compound demonstrates significant antitumor effects in various tumor models, including syngeneic and PD-L1 humanized mice, making it a valuable tool for cancer research and the development of immune checkpoint therapies.
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