PD 144418 oxalate is a selective and potent ligand for the sigma 1 (σ1) receptor, demonstrating a high binding affinity with a Ki value of 0.08 nM. Its selectivity is underscored by minimal affinity for sigma 2 (σ2) and other biological targets, including receptors, ion channels, and enzymes. This compound has potential applications in studying antipsychotic mechanisms and could serve as a valuable tool in neuropharmacological research.
PD 144418 oxalate is a selective and potent ligand for the sigma 1 (σ1) receptor, demonstrating a high binding affinity with a Ki value of 0.08 nM. Its selectivity is underscored by minimal affinity for sigma 2 (σ2) and other biological targets, including receptors, ion channels, and enzymes. This compound has potential applications in studying antipsychotic mechanisms and could serve as a valuable tool in neuropharmacological research.
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