PD 156252

Name: PD 156252
Brand: Adooq Bioscience
SKU: A60274
Rating: 5 (288 reviews)

Catalog No.: A60274

Endothelin Antagonist

PD 156252 is a highly potent endothelin antagonist, primarily targeting the ETA and ETB receptor subtypes. It exhibits enhanced binding affinity with IC50 values of 1.0 nM for rabbit ETA receptors and 40 nM for rat ETB receptors. This compound is valuable for research applications focusing on the endothelin system, cardiovascular studies, and investigations into related pathophysiological conditions.

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PD 156252 175592-65-1 Endothelin Antagonist

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Biological Activity

Description

Product Information

Catalog Num	A60274
Formula	C53H69N7O10
Molecular Weight	964.16
CAS Number	175592-65-1
Sequence	Ac-{d-Bhg}-Leu-Asp-Ile-{(N-Me)Ile}-Trp
Sequence shortening	Ac-{d-Bhg}-LDI-{(N-Me)Ile}-W
SMILES	[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N([C@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(O)=O)=O)[C@H](CC)C)C)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(C)C)=O)(NC(C)=O)C3C=4C(CCC=5C3=CC=CC5)=CC=CC4

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