PD 173955 analog 1

Catalog No.: A28634
EGFR Inhibitor
PD 173955 analog 1 is a selective inhibitor of the epidermal growth factor receptor (EGFR) kinase. This compound demonstrates significant antitumor activity and has been characterized for its toxicological effects. In silico studies have reported an IC50 value of 0.19 μM, indicating its efficacy in modulating EGFR-related signaling pathways, making it a valuable tool for cancer research and therapeutic investigations.
Grouped product items
Size Price Stock Qty
1mg
$155.00
In stock
5mg
$405.00
In stock
10mg
$705.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPD 173955 analog 1 is a selective inhibitor of the epidermal growth factor receptor (EGFR) kinase. This compound demonstrates significant antitumor activity and has been characterized for its toxicological effects. In silico studies have reported an IC50 value of 0.19 μM, indicating its efficacy in modulating EGFR-related signaling pathways, making it a valuable tool for cancer research and therapeutic investigations.
Product Information
Catalog NumA28634
FormulaC21H14Cl2N4O3
Molecular Weight441.27
CAS Number185039-99-0
SMILESO=C(O)C1=CC=CC(NC2=NC=C(C=C(C3=C(Cl)C=CC=C3Cl)C(N4C)=O)C4=N2)=C1
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