PD-L1 inhibitory peptide

Catalog No.: A35732
Inhibitor Peptide
PD-L1 inhibitory peptide is an inhibitor peptide that targets programmed cell death ligand 1 (PD-L1). By binding to PD-L1, it effectively alleviates immunosuppression and enhances the antitumor activity of T cells. This peptide is valuable for cancer research, particularly in the study of immune checkpoint regulation and therapeutic interventions.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPD-L1 inhibitory peptide is an inhibitor peptide that targets programmed cell death ligand 1 (PD-L1). By binding to PD-L1, it effectively alleviates immunosuppression and enhances the antitumor activity of T cells. This peptide is valuable for cancer research, particularly in the study of immune checkpoint regulation and therapeutic interventions.
Product Information
Catalog NumA35732
FormulaC96H135N21O23S
Molecular Weight1983.29
CAS Number1931111-41-9
SequenceAc-Tyr-{NMe-Ala}-Asn-Pro-Dap-Leu-Hyp-Trp-Dab-Trp{CH2COOH}-{NMe-Nle}-{NMe-Nle}-Leu-Cys-Gly-{L-Propargylglycine} (thioether bridge:Tyr1-Cys15)
SMILESOC(CN1C2=CC=CC=C2C(C[C@H]3C(N([C@H](C(N([C@H](C(N[C@H](C(N[C@@H](CSCC(N[C@H](C(N([C@H](C(N[C@H](C(N4[C@](CCC4)([H])C(N[C@H](C(N[C@H](C(N5[C@](C[C@H](C5)O)([H])C(N[C@H](C(N[C@H](C(N3)=O)CCN)=O)CC6=CNC7=CC=CC=C67)=O)=O)CC(C)C)=O)CN)=O)=O)CC(N)=O)=O)C)C)=O)CC8=CC=C(C=C8)O)=O)C(NCC(N[C@H](C(O)=O)CC#C)=O)=O)=O)CC(C)C)=O)CCCC)C)=O)CCCC)C)=O)=C1)=O
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