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PD0166285

Catalog No.: A15863

Wee1/Chk inhibitor

PD0166285

PD0166285 Chemical Structure

CAS NO. 185039-89-8

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$215.00
25 mg
$490.00
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Biological Activity

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
Targets
Wee1 Myt1 Chk1
24 nM72 nM3.4 μM
In vitro DMSO 91 mg/mL (177.58 mM)
Water Insoluble
Ethanol 91 mg/mL (177.58 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.57 mL 195.15 mL
0.5 mM 3.9 mL 19.51 mL 39.03 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15863
Actions Inhibitor
CAS No. 185039-89-8
Formula C26H27Cl2N5O2
M. Wt 512.43
Purity >98%
Synonyms PD-0166285, PD 0166285
SMILES CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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