PD0166285

Catalog No.: A15863

Wee1 inhibitor

PD0166285 Chemical Structure

CAS NO. 185039-89-8

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$215.00
25 mg
$490.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
Targets
Wee1 Myt1 Chk1
24 nM72 nM3.4 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.57 mL 195.15 mL
0.5 mM 3.9 mL 19.51 mL 39.03 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15863
Actions Inhibitor
M. Wt 512.43
Formula C26H27Cl2N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 185039-89-8
Synonyms PD-0166285, PD 0166285
SMILES CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl

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