PDDC is a selective phospholipase inhibitor, specifically targeting neutral sphingomyelinase 2 (nSMase2). This compound effectively reduces tau-induced nSMase2 activity and mitigates ceramide elevation, thereby slowing tau propagation in mouse models. PDDC is utilized in research related to Alzheimer's disease, providing insights into the modulation of neurodegenerative pathways.
PDDC is a selective phospholipase inhibitor, specifically targeting neutral sphingomyelinase 2 (nSMase2). This compound effectively reduces tau-induced nSMase2 activity and mitigates ceramide elevation, thereby slowing tau propagation in mouse models. PDDC is utilized in research related to Alzheimer's disease, providing insights into the modulation of neurodegenerative pathways.
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