PDE1-IN-6

Name: PDE1-IN-6
Brand: Adooq Bioscience
SKU: A31688
Rating: 5 (288 reviews)

Catalog No.: A31688

PDE1 Inhibitor

PDE1-IN-6 is a selective phosphodiesterase 1 (PDE1) inhibitor with an IC50 of 7.5 nM. It effectively inhibits cell proliferation and induces apoptosis in acute myelogenous leukemia (AML) cells. This compound serves as a valuable tool in cancer research, particularly in studies focused on signaling pathways involved in leukemia progression and treatment.

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Biological Activity

Description	PDE1-IN-6 is a selective phosphodiesterase 1 (PDE1) inhibitor with an IC50 of 7.5 nM. It effectively inhibits cell proliferation and induces apoptosis in acute myelogenous leukemia (AML) cells. This compound serves as a valuable tool in cancer research, particularly in studies focused on signaling pathways involved in leukemia progression and treatment.

Product Information

Catalog Num	A31688
Formula	C24H26F2N6O
Molecular Weight	452.50
CAS Number	2877017-16-6
SMILES	CC(C)(N1N=CC2=C1N=C(N(C2=O)CC3=CC=CC(F)=C3)NCCNC4=CC=C(C=C4)F)C

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