PDE11A4-IN-1

Catalog No.: A41971
PDE11A4 Inhibitor
PDE11A4-IN-1 is a selective inhibitor of the phosphodiesterase 11A4 (PDE11A4) enzyme, exhibiting an IC50 of 12 nM. This compound demonstrates strong selectivity for PDE11A4 compared to other phosphodiesterases including PDE1, PDE2, PDE7, PDE8, and PDE9. It is suitable for studies investigating the role of PDE11A4 in various biological processes and potential therapeutic applications in conditions influenced by cyclic nucleotide signaling.
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5mg
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionPDE11A4-IN-1 is a selective inhibitor of the phosphodiesterase 11A4 (PDE11A4) enzyme, exhibiting an IC50 of 12 nM. This compound demonstrates strong selectivity for PDE11A4 compared to other phosphodiesterases including PDE1, PDE2, PDE7, PDE8, and PDE9. It is suitable for studies investigating the role of PDE11A4 in various biological processes and potential therapeutic applications in conditions influenced by cyclic nucleotide signaling.
Product Information
Catalog NumA41971
FormulaC22H22F2N6O
Molecular Weight424.45
CAS Number3027607-92-4
SMILESO=C(C1=C2C(N(N=C2C(F)F)C3=CC=CC=C3)=NC(C4=CC=NN4C)=C1)N(CC)CC
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