PDE12-IN-1 is a potent and selective inhibitor of phosphodiesterase 12 (PDE12), exhibiting an enzyme inhibition pIC50 value of 9.1. This compound effectively elevates levels of 2′,5′-linked adenylate polymers (2-5A), with a pharmacological effect characterized by a pEC50 value of 7.7. PDE12-IN-1 demonstrates significant antiviral activity, making it a valuable tool in biochemical research related to viral pathogenesis and therapeutic interventions.
PDE12-IN-1 is a potent and selective inhibitor of phosphodiesterase 12 (PDE12), exhibiting an enzyme inhibition pIC50 value of 9.1. This compound effectively elevates levels of 2′,5′-linked adenylate polymers (2-5A), with a pharmacological effect characterized by a pEC50 value of 7.7. PDE12-IN-1 demonstrates significant antiviral activity, making it a valuable tool in biochemical research related to viral pathogenesis and therapeutic interventions.
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