PDE4-IN-4

Catalog No.: A41903
PDE4 Inhibitor
PDE4-IN-4 is a selective inhibitor of phosphodiesterase 4 (PDE4) with a pIC50 of 8.8, as well as a dual antagonist of the M3 muscarinic receptor with a pIC50 of 10.2. This compound exhibits significant biological activity in modulating cyclic nucleotide levels, making it valuable for research related to pulmonary diseases. Its dual action allows for exploration of therapeutic pathways in respiratory disorders, providing insights into potential treatment strategies.
Grouped product items
Size Price Stock Qty
5mg
$795.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPDE4-IN-4 is a selective inhibitor of phosphodiesterase 4 (PDE4) with a pIC50 of 8.8, as well as a dual antagonist of the M3 muscarinic receptor with a pIC50 of 10.2. This compound exhibits significant biological activity in modulating cyclic nucleotide levels, making it valuable for research related to pulmonary diseases. Its dual action allows for exploration of therapeutic pathways in respiratory disorders, providing insights into potential treatment strategies.
Product Information
Catalog NumA41903
FormulaC36H37Cl2N3O7S
Molecular Weight726.67
CAS Number1793069-00-7
SMILESO=C(C1=CC=C(CN[C@H](C2=CC=CC=C2)C(O[C@H]3CN4CCC3CC4)=O)S1)O[C@H](C5=CC=C(OC)C(OC)=C5)CC6=C(Cl)C=[N+]([O-])C=C6Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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